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Updated: Aug 14, 2026
07:54
Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Histologic changes in soft palate in patients with obstructive sleep apnea]
E M Llorente Arenas1, E A Vicente González, J M Marín Trigo
1Hospital Universitario Miguel Servet, Zaragoza.
Anales Otorrinolaringologicos Ibero-Americanos
|December 4, 2001
Summary
Obstructive sleep apnea syndrome (OSAS) causes distinct pharyngeal wall damage. Histological analysis revealed significant differences in soft tissue structures between OSAS patients and healthy individuals.
Area of Science:
- Histopathology
- Anatomical Pathology
- Sleep Medicine
Context:
- Obstructive sleep apnea syndrome (OSAS) involves repeated pharyngeal wall injury.
- Microscopic and macroscopic tissue alterations are observed in OSAS patients.
Purpose:
- To conduct a comparative histological study.
- To analyze differences in pharyngeal wall structures between OSAS patients and healthy controls.
Summary:
- A histological comparison was performed on 45 OSAS patients who underwent uvulopalatopharyngoplasty and 10 normal post-mortem palates.
- Eight parameters were assessed to identify significant differences in soft tissue structures.
Impact:
- This study highlights the specific pathological changes in the pharyngeal wall associated with OSAS.
- Findings contribute to understanding the structural basis of OSAS and potential therapeutic targets.
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