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Cognitive subprocesses and schizophrenia. B. Maze tasks.

S Krieger1, S Lis, B Gallhofer

  • 1Centre for Psychiatry, Justus-Liebig-University Giessen, Germany.

Acta Psychiatrica Scandinavica. Supplementum
|December 4, 2001
PubMed
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Schizophrenia patients show improved performance on complex maze tasks under difficult motor conditions, suggesting a shift in attention away from response selection. This effect is reduced by neuroleptic treatment.

Area of Science:

  • Cognitive neuroscience
  • Psychiatry

Background:

  • Previous research indicated response selection deficits in schizophrenia during reaction-time tasks.
  • Cognitive processes in schizophrenia involve complex loops requiring working memory updates.

Purpose of the Study:

  • Investigate subprocesses within cognitive loops in schizophrenia.
  • Examine the role of working memory in complex cognitive tasks for schizophrenia patients.

Main Methods:

  • Maze tasks of varying complexity were administered to drug-naive and treated first-episode schizophrenia patients.
  • Tasks were performed under both easy and difficult motor conditions.
  • Schizophrenia patient groups were compared to age, sex, and education-matched healthy controls.

Main Results:

Related Experiment Videos

  • Patients showed expected performance decline in mazes with alternative routes.
  • Untreated schizophrenia patients demonstrated improved performance under difficult motor conditions.
  • Neuroleptic treatment diminished this performance improvement.

Conclusions:

  • Difficult motor conditions may redirect attention towards motor execution in schizophrenia.
  • This attentional shift could reduce the impact of disturbed response selection.
  • Neuroleptic treatment may modulate this attentional reallocation effect.