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Updated: Aug 11, 2026

Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma
Published on: January 25, 2015
Choroidal melanoma metastatic to the contralateral choroid
A D Singh1, J A Shields, C L Shields
1Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA. arunsingh@eyetumors.com
Purpose:
To report metastasis of choroidal melanoma to the contralateral choroid.
Methods:
Interventional case report. In a 49-year-old Caucasian female, a primary choroidal melanoma, left eye, was diagnosed and treated with Ruthenium-106 plaque radiotherapy. The choroidal melanoma showed excellent regression with flattening of the mass and adjacent chorioretinal atrophy.
Results:
Fifteen years after brachytherapy for choroidal melanoma, left eye, the patient developed a metastatic melanoma to the contralateral choroid as the first sign of metastasis. No history of oculo(dermal) melanocytosis or cutaneous melanoma existed. Systemic evaluation disclosed multiple metastases confined to the liver.
Conclusion:
Metastasis to the contralateral choroid can be the first sign of metastasis from choroidal melanoma.

