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Metastatic adenocarcinoma with rupture through the Bruch membrane simulating a choroidal melanoma
1Department of Ophthalmology, University of Alabama School of Medicine, 700 18th Street S, EFH 601, Birmingham, AL 35233, USA. rwr@uab.edu
Purpose:
To report a case of adenocarcinoma metastatic to the choroid with rupture through the Bruch membrane, thus, simulating a choroidal melanoma.
Methods:
Interventional case report. Evaluation in a university-based clinic, including a complete eye examination, fluorescein angiography, and ultrasonography; oncological evaluation; and eventual enucleation with histopathological study, including immunohistochemical stains.
Results:
A 62-year-old Hispanic female presented with visual loss, right eye, of short duration because of a choroidal mass with retinal detachment. Ultrasonography showed a dome-shaped lesion with an eccentric collar-button projection and medium internal reflectivity, which suggested a choroidal melanoma. Initial systemic evaluation was negative. Severe pain necessitated enucleation, RE, and histopathology of the choroidal mass demonstrated an adenocarcinoma. Further examination revealed a left, upper lobe, nonsmall cell lung carcinoma.
Conclusion:
Metastatic choroidal tumors may present, although rarely, with collar-button configurations.