Related Experiment Video
Updated: Jul 29, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Percutaneous mitral balloon valvotomy: six-year follow-up
H Dighero1, F Zepeda, P Sepúlveda
1Pabellón de Hemodinamia y Cineangiografia, Departamento de Cardiologia, Hospital San Juan de Dios, Huerfanos 3255, Santiago, Chile. hdighero@rdc.cl
Percutaneous mitral valvotomy (PMV) offers a successful treatment for mitral stenosis with a high immediate success rate and low complication incidence. However, restenosis occurs in one-third of patients, with pulmonary hypertension being a key predictor.
Area of Science:
- Cardiology
- Interventional Cardiology
- Valvular Heart Disease
Background:
- Percutaneous mitral valvotomy (PMV) is a less invasive alternative to surgical mitral valve repair for mitral stenosis.
- The efficacy of PMV is influenced by the echocardiographic characteristics of the mitral valve apparatus.
- Assessing long-term outcomes and predictors of restenosis is crucial for patient management.
Purpose of the Study:
- To evaluate the immediate and long-term results of percutaneous mitral valvotomy (PMV).
- To determine the incidence of late adverse events, including restenosis, mitral valve replacement, and death.
- To investigate the correlation between echocardiographic Wilkin's score and late clinical outcomes.
Main Methods:
- A retrospective analysis of 160 PMV procedures performed between 1987 and 1999.
- Inclusion of 96 patients with at least 6 months of follow-up and pre- and post-procedure echocardiographic Wilkin's scores.
- Statistical analysis using Hazard Ratio (HR) and Cox's regression for event prediction.
Main Results:
- PMV achieved a 97% immediate success rate, with 84% considered optimal outcomes.
- Procedure-related complications occurred in 10% of patients, with no procedure-related mortality. Severe mitral regurgitation was seen in 7%.
- Restenosis occurred in 34% of patients during follow-up; this was associated with pulmonary hypertension but not Wilkin's score.
Conclusions:
- PMV demonstrates high immediate success and low procedural complication rates for mitral stenosis.
- Late adverse events were infrequent, and Wilkin's score did not predict long-term outcomes.
- Pulmonary hypertension is a significant clinical predictor for restenosis after PMV.
Related Concept Videos
Mitral Valve Prolapse I: Introduction
Mitral Valve Prolapse II: Assessment and Management
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Regurgitation III: Medical Management
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral Stenosis III: Medical Management

