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Updated: Sep 3, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
Premature rupture of the membranes: an evidence-based approach to clinical care
C S Naylor1, K Gregory, C Hobel
1Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Cedars-Sinai Medical Center, Burns and Allen Research Institute, Los Angeles, California, USA.
Abstract:
Management of the patient with premature rupture of membranes is a relatively common but often perplexing problem frequently faced by the obstetrician. Despite the recent advances in perinatal care, premature membrane rupture, especially in the preterm patient, remains a potentially serious complication with important maternal and fetal implications. This review will address the important questions concerning the management of premature rupture of membranes and will attempt to provide comprehensive answers as they appear in the medical literature.
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