Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiplicative versus additive selection in relation to genome evolution: a simulation study.

G Piganeau1, R Westrelin, B Tourancheau

  • 1Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5558, Biométrie et Biologie Evolutive, Université Claude Bernard Lyon 1, 43 boulevard du 11 novembre 1918, 69622 Villeurbanne, France. piganeau@biomserv.univ-lyon1.fr

Genetical Research
|December 6, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Altrenogest treatment reduces the stress response of three-year-old warmblood mares during their initial equestrian training.

Domestic animal endocrinology·2022
Same author

[A definition of work-related asthma and its social and occupational consequences in adults and teenagers].

Revue des maladies respiratoires·2021
Same author

Effects of blue monochromatic light directed at one eye of pregnant horse mares on gestation, parturition and foal maturity.

Domestic animal endocrinology·2021
Same author

DRESS with eslicarbazepine: The value of allergological exploration.

Annales de dermatologie et de venereologie·2021
Same author

The evaluation of intracranial bypass patency in neurosurgical practice.

Neuro-Chirurgie·2020
Same author

Transient suppression of ovulatory ovarian function in pony mares after treatment with slow-release deslorelin implants.

Domestic animal endocrinology·2020
Same journal

Statistical design and the analysis of gene expression microarray data.

Genetical research·2008
Same journal

Proper experimental design and sound statistical inference win every time: a commentary on 'Statistical design and the analysis of gene expression microarray data' by M. Kathleen Kerr and Gary A. Churchill.

Genetical research·2008
Same journal

Effective population size/adult population size ratios in wildlife: a review.

Genetical research·2008
Same journal

Wild populations are smaller than we think: a commentary on 'Effective population size/adult population size ratios in wildlife: a review' by Richard Frankham.

Genetical research·2008
Same journal

Inbreeding coefficients and coalescence times.

Genetical research·2008
Same journal

Identity and coalescence in structured populations: a commentary on 'Inbreeding coefficients and coalescence times' by Montgomery Slatkin.

Genetical research·2008
See all related articles

Molecular evolution of traits like codon usage can result from mutation and selection. However, selection

Area of Science:

  • Evolutionary biology
  • Molecular evolution
  • Genomics

Background:

  • Molecular quantitative traits evolve due to mutation and selection.
  • Modeling selection-directed genome evolution is computationally intensive.
  • Understanding the interplay of mutation and selection is key to evolutionary genomics.

Purpose of the Study:

  • Investigate the evolution of optimal codon frequency.
  • Analyze the effects of additive and multiplicative selection on linked codons.
  • Assess the efficacy of selection in genome evolution.

Main Methods:

  • Developed models for additive and multiplicative effects of linked codons.
  • Analyzed the impact of the number of selected sites relative to effective population size.

Related Experiment Videos

  • Discussed implications for vertebrate isochore evolution.

    • Main Results:

    • Additive selective effects are ineffective when the number of selected sites exceeds the effective population size.
    • This limitation is relevant given current molecular data on population sizes.
    • The findings challenge assumptions about selection's role in certain genomic contexts.

    Conclusions:

    • Selection's effectiveness in driving genome evolution is constrained by population size and the number of selected sites.
    • The study provides insights into the evolution of molecular traits and genomic structures like isochores.
    • Highlights the importance of considering population genetics in molecular evolution models.