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Updated: Jul 25, 2026

The Bovine Lung in Biomedical Research: Visually Guided Bronchoscopy, Intrabronchial Inoculation and In Vivo Sampling Techniques
Published on: July 3, 2014
Animal models for respiratory chain disease
1Department of Medical Nutrition, Karolinska Institutet, NOVUM, Huddinge Hospital, S-141 86 Huddinge, Sweden. Nils_Goran.Larsson@mednut.ki.se
Abstract:
Elucidation of the pathogenesis in respiratory chain diseases is of great importance for developing specific treatments. The limitations inherent to the use of patient material make studies of human tissues often difficult and the mouse has therefore emerged as a suitable model organism for studies of respiratory chain diseases. In this review, we present an overview of the field and discuss in depth a few examples of animal models reproducing pathology of human disease with primary and secondary respiratory chain involvement.
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