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Related Experiment Videos

Anaplastic meningioma: case report.

A Falavigna1, J A Santos, L Chimelli

  • 1Escola Paulista de Medicina, Federal University of São Paulo, São Paulo, SP, Brazil.

Arquivos De Neuro-Psiquiatria
|December 6, 2001
PubMed
Summary

Malignant meningiomas are rare but challenging brain tumors. This case highlights successful surgical removal and radiation for anaplastic papillary meningioma, emphasizing the need for novel treatments.

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Area of Science:

  • Neuro-oncology
  • Neurosurgery
  • Radiation Oncology

Background:

  • Malignant meningiomas represent 10-15% of intracranial tumors, with limited data on adjuvant therapies.
  • Traditional chemotherapy is largely ineffective for these aggressive neoplasms.
  • External whole brain irradiation is a recommended adjuvant treatment.

Observation:

  • A 67-year-old male presented with seizures, headache, and behavioral changes.
  • Imaging revealed a large left temporo-occipital mass with significant edema.
  • The patient underwent radical surgical resection of the tumor and infiltrated dura.

Findings:

  • The patient remained neurologically intact postoperatively.
  • Adjuvant external whole brain radiation therapy was administered.

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  • This case involves anaplastic papillary meningioma, a rare malignant subtype.

    • Implications:

    • Radical surgical resection followed by adjuvant radiation can be effective for malignant meningiomas.
    • Further research into novel chemotherapeutic agents and immunotherapy is warranted.
    • Multidisciplinary approaches are crucial for managing complex intracranial meningiomas.