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Updated: Jul 25, 2026

11:46
Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
Published on: April 27, 2014
Summary
This study shows habituation therapy effectively treats urinary retention and hypotonicity. Within 20 weeks, urinary residuals decreased to zero, resolving retention issues in patients with neurological disorders.
Area of Science:
- Neurology
- Urology
- Behavioral Medicine
Background:
- Urinary retention and bladder hypotonicity are common in certain neurological disorders.
- Large urinary residuals can lead to complications and decreased quality of life.
Purpose of the Study:
- To evaluate the efficacy of habituation therapy for urinary retention and bladder hypotonicity.
- To demonstrate the application of conditioning therapy in managing neurological bladder dysfunction.
Main Methods:
- Four subjects with urinary retention and bladder hypotonicity were treated using a habituation therapy protocol.
- Urinary residuals and retention status were monitored over a 20-week period.
Main Results:
- Habituation therapy led to an exponential decrease in urinary residuals, reaching 0 ml in all subjects.
- Partial or complete urinary retention resolved completely within 20 weeks of treatment.
Conclusions:
- Habituation therapy is a viable and effective treatment for urinary retention and bladder hypotonicity associated with neurological disorders.
- Conditioning therapy offers a promising approach for managing specific neurological conditions affecting bladder function.
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