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Updated: Aug 11, 2026

Transthoracic Echocardiography in Mice
Published on: May 28, 2010
Tissue Doppler imaging: a useful echocardiographic method for the cardiac sonographer to assess systolic and
1Cardiovascular Imaging and Clinical Research Core Laboratory, Barnes-Jewish Hospital and Washington University School of Medicine, St Louis, Mo 63110, USA. waggonea@msnotes.wustl.edu
Abstract:
Tissue Doppler imaging (TDI) has evolved to become a useful noninvasive method that can complement other echocardiographic techniques in the assessment of left ventricular myocardial velocities in a variety of clinical conditions. Color 2-dimensional and color M-mode TDI are used for quantification of systolic myocardial velocities during myocardial ischemia at rest and with pharmacologic stress testing. Spectral pulsed TDI can provide measurements of regional systolic and diastolic myocardial velocities, and it is particularly useful in the identification of abnormalities of left ventricular diastolic relaxation. This review summarizes the clinical applications of TDI to promote understanding of its utility in the evaluation of left ventricular myocardial function.
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