First experience with a new dedicated ultrasound system for computer-guided large-core breast biopsy

Area of Science:

• Radiology
• Oncology
• Medical Devices

Background:

• Accurate diagnosis of breast lesions is crucial for effective treatment.
• Large core breast biopsy (LCBB) is a standard diagnostic procedure.
• Advancements in imaging and guidance systems aim to improve biopsy accuracy and safety.

Purpose of the Study:

• To describe a novel dedicated ultrasound (US) system for computer-guided large core breast biopsy (LCBB).
• To report the initial clinical experience and evaluate the accuracy and safety of this new system in diagnosing non-palpable breast lesions.

Main Methods:

• The study involved 45 female patients with surgically verified non-palpable breast lesions.
• All biopsies were performed using a new dedicated US system with 14-gauge long-throw needles.
• Histological results from LCBB were compared with open surgical biopsy, and procedure time and complications were recorded.

Main Results:

• The new US system successfully yielded sufficient biopsy material in all 45 lesions.
• Complete histological agreement between LCBB and open surgical biopsy was achieved in 44 out of 45 lesions (97.8%).
• The system demonstrated high accuracy, with only one case of invasive ductal cancer yielding a probable rather than definite diagnosis; no major technical complications were observed.

Conclusions:

• The new dedicated US system for computer-guided LCBB is an accurate and safe method for diagnosing breast lesions.
• This system may offer a promising alternative for physicians with less experience in US-guided LCBB.
• Further evaluation may be warranted to establish its role in routine clinical practice.