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Related Experiment Videos

Scar contractures, hypertrophic scars, and keloids.

A E Brissett1, D A Sherris

  • 1Department of Otorhinolaryngology, Division of Facial Plastic Surgery, Mayo Graduate School of Medicine, Rochester, MN 55905, USA.

Facial Plastic Surgery : FPS
|December 6, 2001
PubMed
Summary

Scar contracture, keloids, and hypertrophic scars (HTSs) arise from abnormal wound healing. Treatment involves patient education, corticosteroid injections, surgery, and pressure dressings for optimal scar management.

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Area of Science:

  • Dermatology
  • Wound Healing
  • Scar Revision

Background:

  • Scar contracture results from a contractile wound-healing process in reepithelialized scars.
  • Keloids and hypertrophic scars (HTSs) are abnormal fibrous tissue outgrowths due to derailed wound healing.
  • The precise incidence of keloids and HTSs is not well-established.

Purpose of the Study:

  • To elucidate the mechanisms and contributing factors in scar contracture, keloid, and hypertrophic scar formation.
  • To outline the standard and individualized treatment protocols for these conditions.

Main Methods:

  • Review of the pathophysiology of scar contracture, keloids, and HTSs.
  • Discussion of contributing factors including biochemical, mechanical, endocrinologic, and genetic elements.

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  • Outline of current treatment strategies.

    • Main Results:

    • Scar contracture involves a contractile process in healed scars.
    • Keloids and HTSs represent derailments in normal wound healing.
    • Multiple factors contribute to abnormal scarring, with trauma often being a misconception as the sole initiator.

    Conclusions:

    • Understanding the multifactorial etiology of abnormal scarring is crucial for effective management.
    • Standard treatment for keloids and HTSs includes corticosteroid injection, surgical excision, pressure dressings, and long-term follow-up.
    • Individualized patient education and treatment plans are essential for managing scar contracture, keloids, and HTSs.