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Clinical pharmacokinetics of non-nucleoside reverse transcriptase inhibitors

P F Smith1, R DiCenzo, G D Morse

  • 1Laboratory for Antiviral Research, University at Buffalo, The State University of New York School of Pharmacy and Pharmaceutical Sciences, Amherst, New York 14260, USA. pfsmith@acsu.buffalo.edu

Clinical Pharmacokinetics
|December 12, 2001
PubMed
Summary

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) offer a unique approach to HIV-1 treatment by allosterically inhibiting viral reverse transcriptase. Understanding their metabolism and drug interactions is crucial for effective combination antiretroviral therapy.

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