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Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
Published on: July 10, 2018
Clear corneal wound infection after phacoemulsification
C B Cosar1, E J Cohen, C J Rapuano
1Cornea Service, Wills Eye Hospital, 900 Walnut St, Philadelphia, PA 19107-5598, USA.
Archives of Ophthalmology (Chicago, Ill. : 1960)
|December 26, 2001
Summary
Clear corneal wound infections following phacoemulsification are serious. Gram-positive bacteria, often resistant to common antibiotics, cause these infections, necessitating targeted treatment for better outcomes.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Surgical Complications
Background:
- Clear corneal wounds are utilized in modern cataract surgery.
- Wound infections represent a significant complication following phacoemulsification procedures.
Purpose of the Study:
- To investigate the characteristics and outcomes of clear corneal wound infections after phacoemulsification.
- To identify causative pathogens and their antibiotic sensitivities.
Main Methods:
- Retrospective review of 7 patient medical records with clear corneal wound infections.
- Analysis of patient demographics, clinical presentation, risk factors, microbial cultures, and treatment responses.
Main Results:
- Infections presented a median of 10 days post-surgery.
- Common pathogens included methicillin-resistant Staphylococcus aureus and Streptococcus pneumoniae.
- Many isolates showed resistance to perioperative fluoroquinolones and tobramycin.
- Topical antibiotics led to healing in most cases, though one required advanced surgical intervention.
Conclusions:
- Clear corneal wound infections are a serious complication of phacoemulsification.
- Gram-positive organisms are the primary cause, often resistant to aminoglycosides and fluoroquinolones.
- Effective treatments include bacitracin and trimethoprim-sulfamethoxazole.
