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Related Experiment Videos

Clear corneal wound infection after phacoemulsification.

C B Cosar1, E J Cohen, C J Rapuano

  • 1Cornea Service, Wills Eye Hospital, 900 Walnut St, Philadelphia, PA 19107-5598, USA.

Archives of Ophthalmology (Chicago, Ill. : 1960)
|December 26, 2001
PubMed
Summary

Clear corneal wound infections following phacoemulsification are serious. Gram-positive bacteria, often resistant to common antibiotics, cause these infections, necessitating targeted treatment for better outcomes.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Surgical Complications

Background:

  • Clear corneal wounds are utilized in modern cataract surgery.
  • Wound infections represent a significant complication following phacoemulsification procedures.

Purpose of the Study:

  • To investigate the characteristics and outcomes of clear corneal wound infections after phacoemulsification.
  • To identify causative pathogens and their antibiotic sensitivities.

Main Methods:

  • Retrospective review of 7 patient medical records with clear corneal wound infections.
  • Analysis of patient demographics, clinical presentation, risk factors, microbial cultures, and treatment responses.

Main Results:

  • Infections presented a median of 10 days post-surgery.

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  • Common pathogens included methicillin-resistant Staphylococcus aureus and Streptococcus pneumoniae.
  • Many isolates showed resistance to perioperative fluoroquinolones and tobramycin.
  • Topical antibiotics led to healing in most cases, though one required advanced surgical intervention.

    • Conclusions:

    • Clear corneal wound infections are a serious complication of phacoemulsification.
    • Gram-positive organisms are the primary cause, often resistant to aminoglycosides and fluoroquinolones.
    • Effective treatments include bacitracin and trimethoprim-sulfamethoxazole.