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Dissecting Host-virus Interaction in Lytic Replication of a Model Herpesvirus
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HIV: master of the host cell

C W Arendt1, D R Littman

  • 1Howard Hughes Medical Institute, Molecular Pathogenesis Program, Skirball Institute of Biomolecular Medicine, New York University Medical Center, New York, NY 10016, USA. littman@saturn.med.nyu.edu

Genome Biology
|December 12, 2001
PubMed
Summary

Human immunodeficiency virus (HIV) manipulates host cells by altering gene expression, largely through the Nef protein. This viral protein acts as a master regulator, broadly impacting cellular responses during infection.

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