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Hydroxychloroquine ototoxicity in a child with idiopathic pulmonary haemosiderosis
Miguel B Coutinho1, Idalinda Duarte
1Department of Otolaryngology, Hospital de Crianças Maria Pia, Rua da Boavista 827, 4050-111, Porto, Portugal. miguelbebiano@hotmail.com
Abstract:
Hydroxychloroquine, a quinoline compound, rarely causes ototoxicity. According to the few reports in existence, hydroxychloroquine-induced ototoxicity occurred following prolonged therapy in adult patients with rheumatoid arthritis and lupus erythematosus. We report a case of unilateral sensorineural hearing loss in a 7-year-old girl with idiopathic pulmonary haemosiderosis, after 2 years of hydroxychloroquine treatment. Sensorineural hearing loss has previously been reported with hydroxychloroquine treatment, but this is the first report in a child and associated to idiopathic pulmonary haemosiderosis and has the characteristic of being unilateral.