Related Experiment Video
Updated: Oct 3, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
cis-dichlorobis(triethylarsine)platinum(II) and cis-dichlorobis(triethylphosphine)platinum(II)
1Inorganic Chemistry 1, Centre for Chemistry and Chemical Engineering, University of Lund, PO Box 124, SE-221 00 Lund, Sweden. stefanus.otto@inorg.lu.se
Abstract:
The crystal structure of cis-[PtCl2(C6H15As)2], (I), is isostructural with a previously reported structure of cis-[PtCl2(C6H15P)2], (II). A new polymorph of (II) is also reported here. Selected geometrical parameters in the arsine complex are Pt-Cl 2.3412 (12) and 2.3498 (13), Pt-As 2.3563 (6) and 2.3630 (6) A, Cl-Pt-Cl 88.74 (5), As-Pt-As 97.85 (2), and Cl-Pt-As 171.37 (4) and 177.45 (4) degrees. Corresponding parameters in the phosphine complex are Pt-Cl 2.364 (2) and 2.374 (2), Pt-P 2.264 (2) and 2.262 (2) A, Cl-Pt-Cl 85.66 (9), P-Pt-P 98.39 (7), and Cl-Pt-P 170.26 (7) and 176.82 (8) degrees.
Related Concept Videos
Stereoisomerism
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...
Radical Substitution: Hydrogenolysis of Alkyl Halides with Tributyltin Hydride
The bonds formed in this reaction are stronger than the bonds broken, making it energetically favorable. The reaction follows a radical chain mechanism similar to radical halogenation reactions,...
Halogenation of Alkenes
Consider the bromination of cyclopentene. Molecular bromine is polarized in the proximity of the π electrons of cyclopentene. An electrophilic bromine atom adds across the double bond, forming a cyclic bromonium ion intermediate.
Preparation and Reactions of Sulfides
Electrophilic Aromatic Substitution: Chlorination and Bromination of Benzene
Hybridization of Atomic Orbitals II
![Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F51444.jpg&w=3840&q=50)
