Related Experiment Video
Updated: Jul 15, 2026
06:08
A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Summary
Thyroid nodularity was found in 1.8% of children surveyed after radiation exposure. While most cases were benign, two malignant neoplasms were identified, highlighting the importance of monitoring thyroid health in children.
Area of Science:
- Environmental Health
- Pediatric Endocrinology
- Nuclear Medicine
Background:
- Assessing thyroid abnormalities in children following radiation exposure is crucial for public health.
- Previous studies have indicated a potential link between fallout radiation and thyroid conditions.
Purpose of the Study:
- To determine the prevalence of thyroid abnormalities, specifically nodularity, in school children exposed to radiation fallout.
- To evaluate the malignancy risk associated with thyroid nodules in pediatric populations.
Main Methods:
- A survey of 5,179 school children across Utah, Nevada, and Arizona was conducted.
- Thyroid examinations were performed to identify nodularity, goiter, thyroiditis, and neoplasms.
Main Results:
- Thyroid nodularity was detected in 98 (1.8%) of the surveyed children.
- Of the nodular cases, 34 were associated with adolescent goiter and 31 with thyroiditis.
- Two malignant neoplasms of the thyroid were discovered, indicating a 2% malignancy risk in incidentally found pediatric thyroid nodules.
Conclusions:
- Radiation exposure from fallout may contribute to thyroid nodularity in children.
- Factors such as discrete nodules, mass growth, singularity, and absence of other thyroid disease warrant further investigation in pediatric thyroid nodules.
- Early detection and monitoring are essential for managing thyroid abnormalities in children exposed to radiation.
More Related Videos
Related Concept Videos
01:21Smooth Endoplasmic Reticulum
Smooth endoplasmic reticulum or smooth ER is a sub-organelle with specialized functions in animal cells and plant cells. It is often associated with the tubule morphology of the endoplasmic reticulum.
The ER provides optimal conditions for synthesizing steroid hormones and lipids, such as phospholipids and triglycerides. Traditionally, lipid metabolism was considered to be a smooth ER function. However, there is no direct evidence to prove that rough ER is completely excluded from lipid...
The ER provides optimal conditions for synthesizing steroid hormones and lipids, such as phospholipids and triglycerides. Traditionally, lipid metabolism was considered to be a smooth ER function. However, there is no direct evidence to prove that rough ER is completely excluded from lipid...
01:30Esophageal Strictures-I: Introduction
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
01:26Esophageal Strictures-II: Clinical Features and Management
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
01:19Cushing Syndrome II: Pathophysiology
Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...
01:27Esophageal Achalasia
Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...
01:23Cirrhosis I: Introduction
Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...