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Updated: Aug 9, 2026
09:16
Eukaryotic Polyribosome Profile Analysis
Published on: June 15, 2010
ERKs weigh in on ribosome mass
1Department of Pharmacology, University of Texas Southwestern Medical School, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
Molecular Cell
|December 14, 2001
Abstract:
In this issue of Molecular Cell, Stefanovsky et al. demonstrate that the activation of the ERK1/2 MAP kinases by growth factors leads to induction of ribosomal gene transcription, through a mechanism dependent on phosphorylation of the upstream binding factor (UBF). This provides a connection between growth factor signaling and increased translation.
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