Related Experiment Videos
A mercapto analogue of 5'-noraristeromycin
Subha R Das1, Stewart W Schneller, Jan Balzarini
1Department of Chemistry, Auburn University, Auburn, AL 36849-5312, USA.
Bioorganic & Medicinal Chemistry
|December 14, 2001
Abstract:
5'-Noraristeromycin and its enantiomer have been found to possess a wide range of antiviral effects. In the search for analogues of and with improved activity, the synthesis of both enantiomers of 5'-mercapto-5'-deoxy-5'-noraristeromycin ( and ) has been accomplished. While (+)-7 was inactive, (-)- did show marginal activity against vaccinia virus, but not any other virus.