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Related Experiment Video

Updated: Jul 24, 2026

Gene Transfer for Ischemic Heart Failure in a Preclinical Model

Gene Transfer for Ischemic Heart Failure in a Preclinical Model

Published on: May 15, 2011

Cardioversion-induced fulminant ischaemic hepatitis.

M Moriel¹, G Morali, E Rosenmann

¹Department of Cardiology, Shaare Zedek Medical Centre, Jerusalem, Israel. cardio@szmc.org.il

European Journal of Gastroenterology & Hepatology

|December 14, 2001

Summary

Fulminant hepatitis can occur in heart failure patients due to ischaemic hepatitis. Cardioversion of atrial fibrillation may transiently reduce cardiac output, inducing this condition.

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Area of Science:

Hepatology
Cardiology

Background:

Ischaemic hepatitis is a potential complication in patients with congestive heart failure.
It is characterized by a rapid increase in transaminases following circulatory compromise.

Observation:

Cardioversion of atrial fibrillation can transiently decrease cardiac output in over a third of patients.
This transient reduction in cardiac output may precipitate ischaemic hepatitis.

Findings:

This case report details the first instance of fulminant ischaemic hepatitis following cardioversion of atrial fibrillation.
The patient presented with acute liver injury secondary to reduced cardiac output.

Implications:

Clinicians should consider ischaemic hepatitis in patients with congestive heart failure presenting with acute liver failure after cardioversion.
Recognizing this association is crucial for timely diagnosis and management of liver injury in cardiac patients.