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Published on: January 20, 2010
Tracheobronchial involvement with Crohn's disease
M T Henry1, L A Davidson, N J Cooke
1Department of Respiratory Medicine, St James's University Hospital, Leeds, UK. pajo@freenetname.co.uk
European Journal of Gastroenterology & Hepatology
|December 14, 2001
Summary
A rare Crohn's disease complication caused severe airway obstruction due to tracheal pseudotumors. Reintroducing corticosteroids rapidly restored airway patency, highlighting their crucial role in managing this condition.
Area of Science:
- Pulmonology
- Gastroenterology
- Immunology
Background:
- Crohn's disease (an inflammatory bowel disease) can have rare extraintestinal manifestations.
- Airway obstruction is an uncommon but severe presentation of such complications.
Observation:
- A young woman with Crohn's disease developed purulent tracheobronchitis and critical upper airway obstruction.
- Bronchoscopy revealed severe tracheal and bronchial pseudotumors and stenosis.
Findings:
- Discontinuation of corticosteroids for quiescent inflammatory bowel disease preceded the onset of endobronchial disease.
- Reintroduction of prednisolone led to a dramatic improvement in airway patency.
Implications:
- This case underscores the potential for severe airway complications in Crohn's disease.
- Corticosteroid management is critical for controlling both bowel inflammation and associated endobronchial disease.
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