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Updated: Jul 27, 2026

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
Published on: January 20, 2010
Tracheobronchial involvement with Crohn's disease
M T Henry1, L A Davidson, N J Cooke
1Department of Respiratory Medicine, St James's University Hospital, Leeds, UK. pajo@freenetname.co.uk
Abstract:
We report the case of a young woman with Crohn's disease of the bowel who presented with a purulent tracheobronchitis and life-threatening upper airway obstruction. Fibreoptic bronchoscopy demonstrated severe tracheal and upper bronchial pseudotumours and stenosis. The role of recent discontinuation of corticosteroids, for quiescent inflammatory bowel disease, in the development of endobronchial disease and the dramatic response in airway patency after reintroduction of prednisolone in this rare complication of Crohn's disease are discussed.
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