Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bitemporal visual field defects in presumed multiple sclerosis.

J G Sacks, O Melen

    JAMA
    |October 6, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Neuro-ophthalmological Complications of Chronic Inflammatory Demyelinating Polyradiculoneuropathy.

    Neuro-ophthalmology (Aeolus Press)·2017
    Same author

    Introduction.

    Postgraduate medicine·2016
    Same author

    Susac syndrome with transient inverted vision.

    Neurology·2004
    Same author

    Lumbar and thoracic epidural blood injections to treat spontaneous intracranial hypotension.

    Anesthesiology·1996
    Same author

    Ocular ischemic syndrome during carotid balloon occlusion testing.

    AJNR. American journal of neuroradiology·1994
    Same author

    Orbital malignant peripheral nerve sheath tumors. Treatment with surgical resection and radiation therapy.

    Journal of clinical neuro-ophthalmology·1993
    Same journal

    WHO Issues Guidelines for Treating Ebola and Marburg Viruses.

    JAMA·2026
    Same journal

    FDA Approves Additional Naloxone Nasal Spray for Opioid Overdose.

    JAMA·2026
    Same journal

    HIV May Hide in More Cells Than Previously Thought-Here's What That Could Mean for a Cure.

    JAMA·2026
    Same journal

    US Dietary Supplement Use Increasing, Especially in Older Adults.

    JAMA·2026
    Same journal

    Heat Stress From Climate Change Surges Globally.

    JAMA·2026
    Same journal

    Strength Training Linked With Lower Cardiovascular Disease Risk in Women.

    JAMA·2026
    See all related articles

    Multiple sclerosis can cause bitemporal hemianopia due to optic chiasm plaques, mimicking tumors. Diagnosis relies on clinical history and neurological signs, not solely imaging.

    Area of Science:

    • Neuro-ophthalmology
    • Neurology
    • Demyelinating Diseases

    Background:

    • Bitemporal hemianopia is typically associated with parasellar tumors affecting the optic chiasm.
    • Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system.

    Observation:

    • Three patients presented with bitemporal hemianopia, initially suspected to be caused by parasellar tumors.
    • The visual field defect in these patients was attributed to demyelinating plaques within the optic chiasm.

    Findings:

    • The diagnosis of multiple sclerosis was established based on a history of relapsing-remitting neurological deficits affecting different central nervous system levels.
    • Normal neuroradiological studies supported the diagnosis of MS in the absence of alternative explanations for the visual field defects.

    Related Experiment Videos

    Implications:

    • In established multiple sclerosis cases with nonprogressive bitemporal visual field defects and preserved visual acuity, extensive neuroimaging may be deferred.
    • This finding highlights the importance of considering MS in the differential diagnosis of bitemporal hemianopia, even when imaging is normal.