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Ginkgo biloba precipitating epileptic seizures
1Health Care of the Elderly, Queen's Medical Centre, Nottingham, UK.
Age and Ageing
|December 18, 2001
Summary
Ginkgo biloba, a popular herbal remedy, may trigger seizures in individuals with epilepsy. Discontinuing the supplement led to seizure control in two reported cases, suggesting a potential adverse effect.
Area of Science:
- Pharmacology
- Neurology
- Herbal Medicine
Background:
- Ginkgo biloba is a widely used herbal supplement.
- It is promoted for various conditions, including memory loss, dementia, and circulatory issues.
- Its popularity is increasing, especially for potential dementia treatment.
Observation:
- Two patients with pre-existing, well-controlled epilepsy experienced recurrent seizures.
- Seizures began within two weeks of starting Ginkgo biloba extract.
- Discontinuation of the herbal remedy resulted in seizure freedom for both patients.
Findings:
- Ginkgo biloba extract may precipitate seizures in susceptible individuals.
- A potential link between Ginkgo biloba use and seizure activity is suggested.
- The herbal remedy's pro-convulsant effect warrants further investigation.
Implications:
- Healthcare providers should be aware of this potential adverse effect.
- Patients with epilepsy should exercise caution when considering Ginkgo biloba.
- Product labeling should highlight the risk of seizures associated with Ginkgo biloba.