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Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
10:24

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry

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Thioredoxin reductase - its role in epidermal redox status

K U Schallreuter1, J M Wood

  • 1Clinical and Experimental Dermatology, Department of Biomedical Sciences, University of Bradford, West Yorkshire, UK. k.schallreuter@bradford.ac.uk

Journal of Photochemistry and Photobiology. B, Biology
|December 18, 2001
PubMed
Summary

The thioredoxin reductase (TR)/thioredoxin (T) system protects skin from oxidative stress. UVB-induced hydrogen peroxide fine-tunes TR activity and impacts melanocyte health, revealing a new role in maintaining skin homeostasis.

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