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Gallbladder pathologies and cholelithiasis

I H Zahrani1, I Mansoor

  • 1Department of Histopathology, King Abdulaziz University Hospital, PO Box 6615, Jeddah 21452, Kingdom of Saudi Arabia. ibm979@hotmail.com

Saudi Medical Journal
|December 18, 2001
PubMed

Insights

Gallbladder diseases, primarily gallstones, are common, with women disproportionately affected. This study analyzed 740 cholecystectomies, finding benign lesions like chronic cholecystitis are most prevalent.

Area of Science:

  • Medical Science
  • Surgical Pathology
  • Epidemiology

Background:

  • Cholecystectomy is a frequent surgical procedure, often indicated for cholelithiasis (gallstones).
  • Understanding the demographics and pathology of gallbladder disease is crucial due to its high incidence and healthcare resource utilization.
  • This study aims to detail gallbladder disease patterns in the Kingdom and compare them with existing literature.

Purpose of the Study:

  • To analyze the age and sex distribution of gallbladder diseases.
  • To identify the prevalence of various gallbladder pathologies, including cholelithiasis.
  • To conduct a comparative analysis with other studies within the Kingdom.

Main Methods:

  • Retrospective analysis of 740 consecutive gallbladder cholecystectomies over 3.5 years.
  • Tabulation of main gallbladder pathologies and the number of gallbladders with stones.
  • Analysis of age and sex distribution for gallbladder pathology and gallstones.

Main Results:

  • A total of 740 cases were reviewed, with females comprising 82% (female to male ratio 4.6:1).
  • Benign lesions accounted for 99% of cases (mean age 36), predominantly chronic cholecystitis (97%).
  • Malignant lesions were rare, constituting 1% (7 cases) with a mean age of 65.

Conclusions:

  • Gallbladder pathologies are highly prevalent, consistent with findings from comparative analyses of 7 other studies.
  • The mean cholecystectomy rate in the Kingdom is approximately 10%.
  • The overall mean age for cholecystectomy patients was 37.05 years, with males averaging 42.26 and females 37.25.
Abstract

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