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Mycobacterium avium intracellulare otitis media
1Department of Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Annals of Diagnostic Pathology
|December 18, 2001
Summary
A rare case of middle ear infection caused by Mycobacterium avium intracellulare in a boy with common variable immunodeficiency is presented. Early diagnosis of this atypical mycobacterial infection is crucial for effective treatment and reduced morbidity.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Immunology
Background:
- Atypical mycobacterial infections of the middle ear are exceptionally rare, with only eight cases documented previously.
- Mycobacterium avium intracellulare accounts for the majority of reported cases.
Observation:
- A case of culture-proven Mycobacterium avium intracellulare otomastoiditis is detailed in an 8-year-old boy.
- The patient exhibited symptoms of otalgia and otorrhea.
- Histopathology revealed acid-fast bacilli within histiocytes.
Findings:
- This case highlights Mycobacterium avium intracellulare as a causative agent in otomastoiditis.
- Common variable immunodeficiency syndrome was identified as an underlying condition in the patient.
Implications:
- Recognizing this rare entity in the differential diagnosis of chronic otorrhea is essential.
- Timely diagnosis and treatment can significantly decrease patient morbidity.