Related Experiment Video
Updated: Jul 24, 2026

New Variations for Strategy Set-shifting in the Rat
Published on: January 23, 2017
Teaching old indicators new tricks
S L Wiskur1, H Ait-Haddou, J J Lavigne
1Department of Chemistry and Biochemistry, The University of Texas at Austin, Austin, Texas 78712, USA.
Abstract:
Most synthetic sensors are designed with covalent attachment between a receptor and a reporter moiety. In this report, we describe the current progress of our use of noncovalently attached indicators to signal binding of analytes. With these systems, analyte binding leads to indicator displacement from the binding cavity, which in turn yields an optical signal modulation. We include previous examples, the strategies involved in our development, and the advantages as well as disadvantages of this method. Finally, our latest research in this field is briefly presented.
Related Concept Videos
Hindsight Biases
Indicators
Design Example: Vintage Mixing Console
The specifications for the pre-amplifier were clear. It needed to amplify the audio signal by a factor of 10, have an input impedance above 10...
Even and Odd Signals
Observational Learning

