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The negative cholecystogram in gallbladder disease.

D R Reid, I M Rogers

    The British Journal of Surgery
    |July 1, 1975
    PubMed
    Summary
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    Gallbladder disease symptoms can be explained by the disappearing gallstone hypothesis, even with negative imaging. Surgery may be recommended for characteristic and severe cases.

    Area of Science:

    • Gastroenterology
    • Radiology
    • Surgical Pathology

    Background:

    • Gallbladder disease diagnosis often relies on imaging, which can miss certain conditions.
    • Symptomatic patients with negative radiological findings present a diagnostic challenge.

    Purpose of the Study:

    • To investigate the 'disappearing stone' hypothesis in radiologically negative gallbladder disease.
    • To determine the utility of cholecystectomy for characteristic and severe presentations.

    Main Methods:

    • Retrospective case series analysis of seventeen patients.
    • Clinical symptom correlation with the 'disappearing stone' hypothesis.

    Main Results:

    • All seventeen cases were explained by the 'disappearing stone' phenomenon.

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  • Symptoms were attributed to transient gallstone presence.

    • Conclusions:

    • The 'disappearing stone' hypothesis provides a plausible explanation for symptoms in radiologically negative gallbladder disease.
    • Cholecystectomy is a viable option for patients with severe and characteristic symptoms, despite negative imaging.