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Updated: May 5, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Cost-effectiveness of coronary stenting in acute myocardial infarction: results from the stent primary angioplasty in
D J Cohen1, D A Taira, R Berezin
1Cardiovascular Data Analysis Center, Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Primary stenting for acute myocardial infarction (AMI) increased initial costs but reduced repeat procedures. Cost-effectiveness improved with updated stent technology, making it favorable if mortality rates are similar to balloon angioplasty.
Area of Science:
- Cardiology
- Health Economics
Background:
- Coronary stenting improves outcomes in acute myocardial infarction (AMI).
- Cost-effectiveness of stenting versus balloon angioplasty for AMI is not well-established.
Purpose of the Study:
- To evaluate the long-term costs and cost-effectiveness of coronary stenting compared to primary balloon angioplasty for AMI.
Main Methods:
- Randomized trial of 900 AMI patients: 448 balloon angioplasty (PTCA), 452 coronary stenting.
- Detailed resource utilization and cost data collected for initial hospitalization and 1-year follow-up.
Main Results:
- Stenting increased procedural costs by ~$2000/patient.
- Stenting significantly reduced repeat revascularization and rehospitalization.
- Overall 1-year costs were ~$1000/patient higher with stenting.
- Cost-effectiveness was $10,550 per repeat revascularization avoided.
- Updated analyses showed a cost differential <$350/patient and improved C/E to $3753 per repeat revascularization avoided.
Conclusions:
- Primary stenting for AMI increased 1-year medical costs compared to primary PTCA.
- Cost-effectiveness depends on the value of avoiding restenosis and relative mortality rates.
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