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Expression of the gene encoding the LIM protein CRP2: a developmental profile
James R Henderson1, Doris Brown, James A Richardson
1Department of Biology/Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112-0840, USA. richard.brown@ucl.ac.uk
Abstract:
Members of the cysteine-rich protein (CRP) family are evolutionarily conserved Lin-11, Isl-1, Mac-3 (LIM) domain proteins that have been implicated in cell differentiation. Here we describe the expression pattern of the CRP family member CRP2 in mouse. Unlike other CRP family members, which are expressed primarily in muscle, CRP2 is more broadly expressed. In addition to expression in vascular smooth muscle cells, we also detect CRP2-specific transcripts in mesenchymal derivatives and several epithelia.