Chemical inhibitors of protein kinases

Therapeutic challenges of kinase and phosphatase inhibition and use in anti-diabetic strategy.

Biochemical Society transactions·2005

Tyrosine kinase inhibitors. 18. 6-Substituted 4-anilinoquinazolines and 4-anilinopyrido[3,4-d]pyrimidines as soluble, irreversible inhibitors of the epidermal growth factor receptor.

Journal of medicinal chemistry·2001

Inhibition of epidermal growth factor receptor tyrosine kinase fails to suppress adenoma formation in ApcMin mice but induces duodenal injury.

Cancer research·2000

Dermatomyositis after interferon alpha treatment.

Medical oncology (Northwood, London, England)·2000

Anticancer efficacy of the irreversible EGFr tyrosine kinase inhibitor PD 0169414 against human tumor xenografts.

Cancer chemotherapy and pharmacology·2000

Tyrosine kinase inhibitors. 16. 6,5,6-tricyclic benzothieno[3, 2-d]pyrimidines and pyrimido[5,4-b-] and -[4,5-b]ĭndoles as potent inhibitors of the epidermal growth factor receptor tyrosine kinase.

Journal of medicinal chemistry·2000

Interfacial Energetics in Metal Halide Perovskite Solar Cells.

Chemical reviews·2026

Low-Dimensional Perovskites and Metal Halides across Structures and Functions: Connectivity, Dimensionality, and Emerging Principles.

Chemical reviews·2026

Milestones in the Elucidation of Heme Biosynthesis.

Chemical reviews·2026

Synthesis, Self-Assembly, Graph Theory, and Applications of Complex Nanoparticle Systems.

Chemical reviews·2026

Recent Advances and Future Perspectives of Proton-Conducting Electrolytes for Reversible Solid Oxide Cells.

Chemical reviews·2026

Rational Design of Copper Nanoclusters for Catalytic Applications.

Chemical reviews·2026

Expanding the chemical biology toolbox: cyclic peptides emerging as versatile chemical probes.

Essays in biochemistry·2026

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development.

Angewandte Chemie (International ed. in English)·2026

Ten-year survival after stenting the proximal left anterior descending coronary artery with new-generation drug-eluting stents.

Cardiovascular intervention and therapeutics·2026

Harnessing snake venom cardiotoxins for antimicrobial peptide discovery.

npj drug discovery·2026

A pyridoxal phosphate-dependent enzyme platform for stereoselective synthesis of γ-tertiary-nitro-noncanonical amino acids.

Nature communications·2026

Pharmacological Activity of Motugivatrep, a Novel Antagonist of Transient Receptor Potential Cation Channel Subfamily V Member 1.

Biological & pharmaceutical bulletin·2026

Related Experiment Videos

Chemical inhibitors of protein kinases

Related Concept Videos

Therapeutic challenges of kinase and phosphatase inhibition and use in anti-diabetic strategy.

Tyrosine kinase inhibitors. 18. 6-Substituted 4-anilinoquinazolines and 4-anilinopyrido[3,4-d]pyrimidines as soluble, irreversible inhibitors of the epidermal growth factor receptor.

Inhibition of epidermal growth factor receptor tyrosine kinase fails to suppress adenoma formation in ApcMin mice but induces duodenal injury.

Dermatomyositis after interferon alpha treatment.

Anticancer efficacy of the irreversible EGFr tyrosine kinase inhibitor PD 0169414 against human tumor xenografts.

Tyrosine kinase inhibitors. 16. 6,5,6-tricyclic benzothieno[3, 2-d]pyrimidines and pyrimido[5,4-b-] and -[4,5-b]ĭndoles as potent inhibitors of the epidermal growth factor receptor tyrosine kinase.

Interfacial Energetics in Metal Halide Perovskite Solar Cells.

Low-Dimensional Perovskites and Metal Halides across Structures and Functions: Connectivity, Dimensionality, and Emerging Principles.

Milestones in the Elucidation of Heme Biosynthesis.

Synthesis, Self-Assembly, Graph Theory, and Applications of Complex Nanoparticle Systems.

Recent Advances and Future Perspectives of Proton-Conducting Electrolytes for Reversible Solid Oxide Cells.

Rational Design of Copper Nanoclusters for Catalytic Applications.

Expanding the chemical biology toolbox: cyclic peptides emerging as versatile chemical probes.

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development.

Ten-year survival after stenting the proximal left anterior descending coronary artery with new-generation drug-eluting stents.

Harnessing snake venom cardiotoxins for antimicrobial peptide discovery.

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Pharmacological Activity of Motugivatrep, a Novel Antagonist of Transient Receptor Potential Cation Channel Subfamily V Member 1.

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Chemical inhibitors of protein kinases

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