Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diarrhoeagenic Escherichia coli--an emerging problem?

S C Clarke1

  • 1Scottish Meningococcus and Pneumococcus Reference Laboratory, Department of Microbiology, Stobhill Hospital, Balornock Road, G21 3UW, Glasgow, United Kingdom. stuart.clarke@northglasgow.scot.nhs.uk

Diagnostic Microbiology and Infectious Disease
|December 26, 2001
PubMed
Summary

Diarrheagenic Escherichia coli cause significant global illness. Understanding their diverse types and virulence factors is crucial for developing effective treatments and vaccines against these challenging pathogens.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

International links between Streptococcus pneumoniae vaccine serotype 4 sequence type (ST) 801 in Northern European shipyard outbreaks of invasive pneumococcal disease.

Vaccine·2022
Same author

Serotype prevalence of Streptococcus pneumoniae in Malaysia - the need for carriage studies.

The Medical journal of Malaysia·2016
Same author

Nasopharyngeal Bacterial Carriage in the Conjugate Vaccine Era with a Focus on Pneumococci.

Journal of immunology research·2015
Same author

A patient safety checklist for the cardiac catheterisation laboratory.

Heart (British Cardiac Society)·2014
Same author

Evaluation of swabbing methods for estimating the prevalence of bacterial carriage in the upper respiratory tract: a cross sectional study.

BMJ open·2014
Same author

Evaluation of PCR-based approach for serotype determination of Streptococcus pneumoniae.

Tropical biomedicine·2013

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Diarrhea is a major global health concern, with diarrheagenic Escherichia coli being a primary cause.
  • These pathogens pose significant challenges, particularly in developed nations, manifesting as traveler's diarrhea and hemorrhagic colitis.

Purpose of the Study:

  • To review the classification and known virulence determinants of diarrheagenic E. coli.
  • To highlight the ongoing challenges in combating these infections due to incompletely understood virulence factors and lack of vaccines.

Main Methods:

  • Literature review of existing research on diarrheagenic E. coli.
  • Analysis of the seven recognized classes of diarrheagenic E. coli and their associated virulence factors.

Related Experiment Videos

Main Results:

  • Identified seven classes: EPEC, EHEC, EIEC, ETEC, EAggEC, DHEC, and CDT-producing E. coli.
  • Noted that while some virulence factors are known, many remain to be fully elucidated.
  • Confirmed that some classes produce toxins, contributing to their pathogenicity.

Conclusions:

  • Diarrheagenic E. coli represent a substantial and evolving public health problem.
  • The incomplete understanding of virulence factors and the absence of effective vaccines necessitate further research and development.