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ToolShop: prerelease inspections for protein structure prediction servers.
1Bioinformatics Laboratory, BioInfoBank Institute, ul. Limanowskiego 24A, 60-744 Poznan, Poland. leszek@bioinfo.pl
Bioinformatics (Oxford, England)
|December 26, 2001
Summary
ToolShop allows users to compare new protein structure prediction servers against established ones using 203 proteins and over 20 programs. This comprehensive evaluation ensures high-quality predictions before public release.
Area of Science:
- Computational biology
- Structural bioinformatics
- Protein structure prediction
Background:
- The ToolShop server provides a platform for evaluating protein tertiary structure prediction servers.
- It facilitates comparison with existing popular servers prior to public release.
Purpose of the Study:
- To offer a robust method for assessing the performance of novel protein structure prediction servers.
- To enable comparative analysis against a wide range of established prediction tools.
Main Methods:
- Utilizes a benchmark set of 203 proteins for evaluation.
- Compares predicted models against outputs from over 20 other prediction programs.
- Employs various established assessment procedures for model quality evaluation.
Main Results:
- The evaluation process involves a comprehensive comparison of prediction accuracy.
- The system is designed to provide a thorough assessment within approximately one week.
Conclusions:
- ToolShop offers a valuable service for the protein structure prediction community.
- It aids developers in refining and validating their prediction servers.