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MIPS: a database for genomes and protein sequences.

H W Mewes1, D Frishman, U Güldener

  • 1Institute for Bioinformatics (MIPS), GSF National Research Center for Environment and Health, Ingolstaedter Landstrasse 1, D-85764 Neuherberg, Germany. w.mewes@gsf.de

Nucleic Acids Research
|December 26, 2001
PubMed
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The Munich Information Center for Protein Sequences (MIPS-GSF) systematically provides updated genome information and analysis tools. This includes curated databases for yeast, Neurospora, and plant genomes, enhancing protein sequence analysis and functional annotation.

Area of Science:

  • Bioinformatics
  • Genomics
  • Proteomics

Background:

  • The Munich Information Center for Protein Sequences (MIPS-GSF) is a key resource for genome-related data.
  • It supports national and European sequencing and functional analysis initiatives.
  • MIPS develops and maintains genome-specific databases with automated and manual annotations.

Purpose of the Study:

  • To update information on various genome databases managed by MIPS.
  • To highlight MIPS's role in functional annotation and protein sequence analysis.
  • To provide access to MIPS resources via their World Wide Web server.

Main Methods:

  • Systematic data collection and curation for multiple genomes.
  • Development of classification schemes for protein sequence annotation.

Related Experiment Videos

  • Provision of bioinformatics tools for comprehensive protein analysis.

    • Main Results:

    • Updated information on yeast (CYGD), Neurospora crassa (MNCDB), and PEDANT genomes.
    • Inclusion of human EST clusters (HIB) and German Human Genome Project (DHGP) data.
    • Details on project-specific databases for GABI and HNB networks.

    Conclusions:

    • MIPS-GSF continues to be a vital resource for genomic and proteomic data.
    • The integrated databases and analysis tools facilitate research in various model organisms.
    • All MIPS resources are accessible online for the scientific community.