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YPL.db: the Yeast Protein Localization database.

Georg Habeler1, Klaus Natter, Gerhard G Thallinger

  • 1Institute of Biomedical Engineering, Graz University of Technology, Krenngasse 37, 8010 Graz, Austria.

Nucleic Acids Research
|December 26, 2001
PubMed
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The Yeast Protein Localization database (YPL.db) archives yeast protein localization data from microscopy. This resource aids in characterizing protein locations and provides links to other yeast databases.

Area of Science:

  • Cell Biology
  • Biochemistry
  • Bioinformatics

Background:

  • Understanding protein localization is crucial for deciphering cellular functions.
  • Microscopic analyses provide essential data on where proteins reside within cells.
  • Existing databases may lack comprehensive, standardized localization information.

Purpose of the Study:

  • To establish a centralized, searchable database for yeast protein localization data.
  • To archive experimental parameters and microscopy images for reproducibility.
  • To facilitate the characterization of known and unknown protein localization patterns.

Main Methods:

  • Data compilation from microscopic analyses of yeast proteins.
  • Storage of experimental parameters, localization data, and images in a relational database.

Related Experiment Videos

  • Implementation of query functions based on gene name, localization, and experimental conditions.

    • Main Results:

    • The Yeast Protein Localization database (YPL.db) is established, containing detailed localization information.
    • Standardized experimental parameters ensure data integrity and comparability.
    • The database supports queries for gene name, protein localization, and growth conditions.

    Conclusions:

    • YPL.db serves as a valuable structural reference for yeast protein localization studies.
    • The database enhances the characterization of ambiguous or novel localization patterns.
    • Integrated links to MIPS, YPD, and SGD provide comprehensive access to yeast information.