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Update of AMmtDB: a database of multi-aligned Metazoa mitochondrial DNA sequences
Cecilia Lanave1, Flavio Licciulli, Mariateresa De Robertis
1Centro di Studio sui Mitocondri e Metabolismo Energetico CNR, Via Amendola 165/A, 70126 Bari, Italy. cecilia@area.ba.cnr.it
Abstract:
The AMmtDB database (http://bighost.area.ba.cnr.it/mitochondriome) has been updated by collecting the multi-aligned sequences of Chordata and Invertebrata mitochondrial genes coding for proteins and tRNAs. Links to the multi-aligned mtDNA intraspecies variants, collected in VarMmtDB at the Mitochondriome web site, have been introduced. The genes coding for proteins are multi-aligned based on the translated sequences and both the nucleotide and amino acid multi-alignments are provided. AMmtDB data selected through SRS can be viewed and managed using GeneDoc or other programs for the management of multi-aligned data depending on the user's operative system. The multiple alignments have been produced with CLUSTALW and PILEUP programs and then carefully optimized manually.