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READ: RIKEN Expression Array Database.

Hidemasa Bono1, Takeya Kasukawa, Yoshihide Hayashizaki

  • 1Laboratory for Genome Exploration Research Group, RIKEN Genomic Sciences Center (GSC), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

Nucleic Acids Research
|December 26, 2001
PubMed
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The RIKEN Expression Array Database (READ) stores mouse microarray data, offering tools for researchers to analyze gene expression profiles and discover biologically significant information. It aids the RIKEN mouse encyclopedia project by providing access to expression data and integrated search functionalities.

Area of Science:

  • Bioinformatics
  • Genomics
  • Molecular Biology

Background:

  • Microarray technology generates large-scale gene expression data.
  • Efficient data storage and analysis are crucial for biological research.
  • The RIKEN mouse encyclopedia project aims to comprehensively catalog mouse biology.

Purpose of the Study:

  • To establish a centralized database for RIKEN mouse cDNA microarray data.
  • To provide researchers with web-based tools for data retrieval, analysis, and visualization.
  • To facilitate the discovery of biologically important information from gene expression profiles.

Main Methods:

  • Development of the RIKEN Expression Array Database (READ).
  • Integration of experimental microarray data and associated information.

Related Experiment Videos

  • Implementation of web interfaces for data access and analysis.
  • Incorporation of gene information primarily from the FANTOM database.
  • Development of the READ integrates gene expression neighbor (RINGENE) search tool.

    • Main Results:

    • READ provides a robust platform for storing and accessing mouse gene expression data.
    • Web interfaces enable researchers to retrieve, analyze, and visualize expression profiles.
    • The RINGENE tool allows for the identification of genes with similar expression patterns.
    • READ serves as a valuable resource for the RIKEN mouse encyclopedia project.

    Conclusions:

    • READ is a critical resource for researchers studying mouse gene expression.
    • The database enhances the utility of microarray data through integrated analysis tools.
    • READ supports ongoing research initiatives, including the RIKEN mouse encyclopedia project.