Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

ASTRAL compendium enhancements.

John-Marc Chandonia1, Nigel S Walker, Loredana Lo Conte

  • 1Berkeley Structural Genomics Center, Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.

Nucleic Acids Research
|December 26, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advancing impact and access: Introducing <i>JNIS Advances</i>.

Journal of neurointerventional surgery·2026
Same author

Reclassification and weighting of multiple causes of death: US death certificates 2003-2023.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Idiopathic Acquired Hemophilia A With High-Titer Factor VIII Inhibitor in an Elderly Patient: A Case Report.

Cureus·2026
Same author

On the state of protein function prediction: a report on the fourth CAFA challenge.

bioRxiv : the preprint server for biology·2026
Same author

Advances in Protein Function Prediction from the Fifth CAFA Challenge.

bioRxiv : the preprint server for biology·2026
Same author

Calibration of in-frame indel variant effect predictors for clinical variant classification.

bioRxiv : the preprint server for biology·2026
Same journal

Correction to 'New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress'.

Nucleic acids research·2026
Same journal

VeloRM: disentangling pre- and post-splicing RNA modification dynamics at single-cell resolution.

Nucleic acids research·2026
Same journal

Accessibility of telomeric overhangs to stabilizing small-molecule ligands.

Nucleic acids research·2026
Same journal

Multivalent interactions mediate SNAIL transcription factor stimulation of the nucleosome deacetylase activity of the CoREST complex.

Nucleic acids research·2026
Same journal

Genome-wide mapping of DNA G-quadruplexes in Trypanosoma brucei chromatin reveals enrichment in coding regions and transcription start sites.

Nucleic acids research·2026
Same journal

Correction to 'The Gene Ontology knowledgebase in 2026'.

Nucleic acids research·2026
See all related articles

The ASTRAL compendium now offers double the protein domain sequences and new databases for structural analysis. These resources aid in studying protein sequences and domain structures, enhancing bioinformatics research.

Area of Science:

  • Bioinformatics
  • Structural Biology
  • Computational Biology

Background:

  • The ASTRAL compendium is a valuable resource for analyzing protein structures using sequence data.
  • It is derived from the SCOP database and provides sequences for protein domains.
  • Previous versions have been available for two years.

Purpose of the Study:

  • To detail the significant updates and improvements made to the ASTRAL compendium.
  • To highlight new databases and expanded sequence data for protein structure analysis.
  • To introduce the Rapid Access Format (RAF) database and its utility.

Main Methods:

  • Expanded the protein domain sequence count from 15,190 to 30,867.
  • Integrated additional databases, including the Rapid Access Format (RAF).

Related Experiment Videos

  • Developed a method for creating 'genetic domain' sequences from multi-chain SCOP domains.

    • Main Results:

    • The ASTRAL compendium's size has doubled, offering a more comprehensive dataset.
    • The RAF database provides curated mappings for rapid automated analysis of protein sequences.
    • New libraries include both original SCOP sequences and novel genetic domain sequences.
    • Representative subsets based on similarity criteria are now available.

    Conclusions:

    • The updated ASTRAL compendium offers enhanced resources for protein sequence and structure analysis.
    • The inclusion of genetic domain sequences and the RAF database improves data accessibility and utility.
    • ASTRAL continues to be a crucial tool for researchers in structural bioinformatics.