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PLANT-PIs: a database for plant protease inhibitors and their genes
F De Leo1, M Volpicella, F Licciulli
1Dipartimento di Biochimica e Biologia Molecolare, Università di Bari, Via Amendola 165/A, Bari, Italy.
Nucleic Acids Research
|December 26, 2001
Summary
PLANT-PIs is a new database for plant protease inhibitors (PIs) and their genes. It offers integrated information on PI function and sequences, aiding research accessibility.
Area of Science:
- Biochemistry
- Genomics
- Bioinformatics
Background:
- Plant protease inhibitors (PIs) play crucial roles in plant defense and development.
- Efficient access to curated information on PIs and their associated genes is essential for researchers.
- Existing resources may lack comprehensive integration of functional and sequence data.
Purpose of the Study:
- To develop and present PLANT-PIs, a centralized database for plant protease inhibitors.
- To facilitate the retrieval of information on plant PIs, including their functional properties and related genes.
- To provide links to sequence databases and literature-derived functional summaries for each PI.
Main Methods:
- Database development leveraging literature curation.
- Integration of data from sequence databases.
- Web accessibility through a dedicated URL.
Main Results:
- PLANT-PIs contains information on 351 plant PIs and associated isoinhibitors.
- Each entry includes links to sequence databases.
- Functional properties of PIs and their mutants are summarized from scientific literature.
Conclusions:
- PLANT-PIs serves as a valuable resource for plant protease inhibitor research.
- The database enhances accessibility to integrated PI data.
- Facilitates further investigation into plant defense mechanisms and protein interactions.