Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Modeling static and dynamic human cardiovascular responses to exercise.

R W Stremel, E M Bernauer, L W Harter

    Computer Programs in Biomedicine
    |August 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Diagnostic utility of microarray testing in pregnancy loss.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2015
    Same author

    Further Evidence of Contrasting Phenotypes Caused by Reciprocal Deletions and Duplications: Duplication of NSD1 Causes Growth Retardation and Microcephaly.

    Molecular syndromology·2013
    Same author

    Investigation of TBR1 Hemizygosity: Four Individuals with 2q24 Microdeletions.

    Molecular syndromology·2012
    Same author

    Variability of yellow tulp (Moraea pallida Bak.) toxicity.

    Journal of the South African Veterinary Association·2011
    Same author

    Microarray detection of multiple recurring submicroscopic chromosomal aberrations in pediatric T-cell acute lymphoblastic leukemia.

    Leukemia·2011
    Same author

    Evaluation of activated charcoal as treatment for Yellow tulp (Moraea pallida) poisoning in cattle.

    Journal of the South African Veterinary Association·2010

    This study models human physiological responses during exercise, incorporating dynamic characteristics of heart rate and cardiac output. The findings reveal a first-order system with a six-minute time constant, improving exercise stress modeling.

    Area of Science:

    • Human physiology
    • Exercise science
    • Systems biology

    Background:

    • Existing human performance models use static relationships for oxygen consumption and blood flow.
    • Steady-state models approximate heart rate (HTRT) using cardiac output (CO) and stroke volume (SV).
    • Transient characteristics are crucial for accurately modeling physiological adjustments to exercise stress.

    Purpose of the Study:

    • To incorporate dynamic transient characteristics into a human performance model.
    • To accurately represent the physiological systems' adjustment to exercise stress.
    • To develop a more complex yet physiologically accurate model.

    Main Methods:

    • Experiments involving step and sinusoidal work forcing were conducted.
    • Dynamic transient characteristics of heart rate, stroke volume, and cardiac output were measured.

    Related Experiment Videos

  • Gain and phase relationships were analyzed to identify system order and time constants.

    • Main Results:

    • The study identified a probable first-order system governing these cardiovascular parameters.
    • A time constant of six minutes was determined for the system.
    • The dynamic model provides a more accurate representation of physiological responses.

    Conclusions:

    • Dynamic modeling significantly enhances the accuracy of human performance models.
    • The identified first-order system with a six-minute time constant offers a refined understanding of exercise physiology.
    • This approach improves the simulation of the body's response to varying exercise loads.