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Mechanisms of epileptogenicity in focal malformations caused by abnormal cortical development
1Section of Epilepsy, Department of Neurology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. yingz@ccf.org
Neurosurgery Clinics of North America
|January 5, 2002
Abstract:
In this article, the authors review the cellular mechanisms of epileptogenicity in malformations caused by abnormalities of cortical development as related to neuronal excitation, reduced inhibition, disorganized synaptic connections, and glial function (or dysfunction).