Related Experiment Videos
No significant increase in chromosome aberrations and sister chromatid exchanges in cultured human lymphocytes
Eyyüp Rencüzoğullari1, Hasan Basri Ila, Mehmet Topaktaş
1Cukurova University, Faculty of Arts and Sciences, Biology Department, Adana, Turkey.
Teratogenesis, Carcinogenesis, and Mutagenesis
|January 5, 2002
Abstract:
In this study, the chromosomal aberrations (CAs) and sister chromatid exchanges (SCEs) were investigated in human lymphocytes treated with spiramycin antibiotic (trade name, rovamycin). Spiramycin did not induce the CAs and SCEs, and also did not decrease the mitotic index (MI). However, spiramycin decreased the replication index (RI) only at 48 h treatment times.