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Multishot diffusion-weighted FSE using PROPELLER MRI
James G Pipe1, Victoria G Farthing, Kirsten P Forbes
1MRI Department, Barrow Neurological Institute, Phoenix, Arizona 85013, USA.
Abstract:
A method for obtaining diffusion-weighted images that are free from the artifacts associated with echo-planar acquisitions, such as signal pile-up and geometric warping, is introduced. It uses an ungated, multishot fast spin-echo (FSE) acquisition that is self-navigated. The phase of the refocusing pulses is alternated to minimize non-Carr-Purcell-Meiboom-Gill (CPMG) artifacts. Several reconstruction methods are combined to make this method robust against motion artifacts. Examples are shown of clinical diffusion-weighted imaging and high-resolution diffusion tensor imaging.
Insights
This study introduces a novel self-navigated fast spin-echo method for artifact-free diffusion-weighted imaging. It enhances image quality by minimizing common echo-planar imaging artifacts and motion issues.
Area of Science:
- Magnetic Resonance Imaging
- Medical Imaging Physics
Background:
- Echo-planar imaging (EPI) is prone to artifacts like signal pile-up and geometric distortion.
- These artifacts limit the diagnostic quality of diffusion-weighted images (DWIs).
Purpose of the Study:
- To develop a diffusion-weighted imaging method free from EPI-associated artifacts.
- To improve robustness against motion artifacts for clearer imaging.
Main Methods:
- Utilized an ungated, multishot fast spin-echo (FSE) acquisition.
- Employed self-navigation techniques for motion correction.
- Alternated refocusing pulse phases to minimize non-Carr-Purcell-Meiboom-Gill (CPMG) artifacts.
- Integrated multiple reconstruction methods for enhanced motion robustness.
Main Results:
- Successfully obtained diffusion-weighted images without common EPI artifacts.
- Demonstrated high-resolution diffusion tensor imaging (DTI) capabilities.
- Showcased clinical applicability of the developed method.
Conclusions:
- The proposed self-navigated multishot FSE method offers artifact-free diffusion-weighted imaging.
- This technique improves image quality and motion robustness in MRI.
- It holds promise for advanced clinical DWI and DTI applications.