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Leakage around voice prosthesis in laryngectomees: treatment with local GM-CSF
G Margolin1, G Masucci, R Kuylenstierna
1Department of Othorhinolaryngology and Head and Neck Surgery, Karolinska Hospital, SE-17176 Stockholm, Sweden. gregory.margolin@ks.se
Objectives:
The aim of this study was to investigate the possibility of treating leakage around voice prosthesis by local injection of granulocyte-macrophage colony-stimulating factor (GM-CSF).
Study Design:
Three patients with nonhealing leaking tracheoesophageal (TE) fistula, resistant to common treatment, were treated with local GM-CSF.
Material And Methods:
Fistula size was measured and photo documented before and after treatment.
Result:
In all three patients, the fistula shrank, and the leakage ceased. No side effects were observed.
Conclusion:
Local injection with GM-CSF seems to be a simple and effective way of decreasing a leaking TE-fistula in laryngectomized patients. A great advantage was that the procedure could be done with the voice prosthesis in place.