Complexation of several benzimidazole-type fungicides with alpha- and beta-cyclodextrins

Minerva Lezcano¹, Wajih Al-Soufi, Mercedes Novo

¹Departamentos de Química Física y Física Aplicada, Facultade de Ciencias, Universidade de Santiago de Compostela, E-27002 Lugo, Spain.

Journal of Agricultural and Food Chemistry

|January 5, 2002

Abstract:

The potential increase in water solubility of three benzimidazole-type fungicides (thiabendazole, carbendazim, and fuberidazole) due to complexation with alpha- and beta-cyclodextrins was investigated. Fluorescence emission spectra of the fungicides in the presence of different concentrations of the cyclodextrins were measured. Analysis of these spectra by the method of principal components global analysis (PCGA) yielded precise values for the association constants and the emission spectra of the fungicide-cyclodextrin inclusion complexes. Phase-solubility diagrams confirmed the formation of inclusion complexes between each of the fungicides and beta-cyclodextrin and showed significant increases of their solubilities due to complexation.

Related Experiment Videos

Complexation of several benzimidazole-type fungicides with alpha- and beta-cyclodextrins

Related Concept Videos

Critical role of Cas9 aggregation on in vitro DNA cleavage.

Spanish Adaptation and Validation of the General Attitudes Towards Artificial Intelligence Scale (GAAIS).

Comparative Analysis of CRISPR/Cas9 Delivery Methods in Marine Teleost Cell Lines.

Intrinsic visible emission of amyloid-β oligomers: a potential tool for early alzheimer's diagnosis.

CRISPR/Cas9 Delivery Systems to Enhance Gene Editing Efficiency.

Amyloid capture and aggregation inhibition by human serum albumin.

Anti-inflammatory Diterpenoids and Sesquiterpenoids from the Rhizomes of Shell Ginger (Alpinia zerumbet).

Application of Ambient Ionization Mass Spectrometry for the Screening of Pesticide Contaminants on Cannabis Plant Materials.

MOFs-Loaded Nanopesticides for Sustainable Agriculture Application.

Structure of In Vitro Digestion Residues from High-Amylose Starch Impacts Colonic Microbial Composition and Metabolic Activity.

Discovery, Optimization, and Biological Evaluation of Novel (1,2,4-Triazol-1-yl)propan-2-ol Derivatives as Potent Demethylation Inhibitors.

Fenugreek Seeds, Leaves, and Derived Ingredients: Chemistry, Structure-Function Relationships, and Food-System Applications.

Structure prediction and drug screening targeting monkeypox virus polymerase and surface proteins.

Discovery, validation, and mechanistic investigation of 5-fluorobenzothiazol-2-amine as a potential lead compound for pre-emergence herbicide development.

Design, synthesis, antifungal activity and preliminary mechanistic study of benzimidazole-containing cinnamamide derivatives against phytopathogenic fungi.

6-(2-Hydroxybenzoyl)pyrazolo[1,5-a]pyrimidine-3‑carbonitriles as novel reactive oxygen species-generating anticancer agents inducing ER stress and DNA damage in EGFR-mutant non-small cell lung cancer.

Online proteolysis and specific affinity enrichment of ACE inhibitory peptides on a magnetic nanoplatform from Torreya grandis protein.

Comparative phytochemical profiling of three medicinal Polygonaceae plants using integrated molecular networking and SIRIUS-guided annotation: Implications for chemotaxonomy.

Related Experiment Videos

Complexation of several benzimidazole-type fungicides with alpha- and beta-cyclodextrins

Abstract:

Related Concept Videos

Related Articles