Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Developmental genes and heart disease].

P Ruiz-Lozano1, T Nakamura, K R Chien

  • 1Universidad de California, San Diego, USA.

Revista Espanola De Cardiologia
|January 5, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Superselective endovascular tissue access using trans-vessel wall technique: feasibility study for treatment applications in heart, pancreas and kidney in swine.

Journal of internal medicine·2018
Same author

Effect of geraniol on rat cardiomyocytes and its potential use as a cardioprotective natural compound.

Life sciences·2017
Same author

Lessons from lincoln.

Trends in cardiovascular medicine·2011
Same author

The polymerase chain reaction (PCR) and cardiovascular diagnosis.

Trends in cardiovascular medicine·2011
Same author

Molecular cardiology in the postmolecular era Turning toward complexity.

Trends in cardiovascular medicine·2011
Same author

Multipotent islet-1 cardiovascular progenitors in development and disease.

Cold Spring Harbor symposia on quantitative biology·2009

Recent cardiology research highlights developmental genes in adult heart function and programmed cell death in cardiac hypertrophy. This review explores key factors in cardiac morphogenesis using gene mutation analysis in transgenic mice.

Area of Science:

  • Cardiology
  • Developmental Biology
  • Molecular Genetics

Context:

  • Recent advances in cardiology underscore the role of developmental genes in adult cardiac physiology.
  • Programmed cell death is identified as a key regulator in the transition from cardiac adaptation to hypertrophy.
  • Previous studies focused on molecular markers for cardiac determination and differentiation.

Purpose:

  • To review key factors in cardiac morphogenesis.
  • To examine the role of gene mutations in understanding cardiac defects.
  • To connect developmental processes with adult cardiac function.

Summary:

  • The past three years have been critical for understanding developmental gene relevance in adult cardiac physiology.
  • Endogenous control of programmed cell death marks the transition between normal adaptation and cardiac hypertrophy.

Related Experiment Videos

  • Analysis of gene mutations in transgenic mice provides new insights into cardiac shape and function defects.

    • Impact:

    • Provides a new perspective on the nature of cardiac defects (shape and function).
    • Highlights the importance of developmental genes in adult heart health.
    • Offers a foundation for future research into cardiac morphogenesis and disease.